Disney's Epic Mickey, currently a Wii exclusive, may head to other formats in the future in the advent of other motion controllers.
Warren Spector's unique take on the whole Mickey Mouse concept is being carefully painted for Nintendo's wide-audience control, the main reason being the Wii Remote's use to literally paint things in the game. It's "completely intuitive to people", said Disney's Graham Hopper in a discussion with Gamasutra, though if the studio had started later then they may have considered their options differently.
We have a very large audience base that has Wiis in their home. That's not to say that we won't go to other platforms [in the future].
On a related note, Hopper was quizzed on the constantly demanded Kingdom Hearts III, refusing to comment. He did acknowledge that the franchise as a whole is doing well, and that Disney are using lessons learnt from the success of the series to fuel Epic Mickey development.